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US 6,143,796 AGranted
Method for reducing development of free radical induced malignancies
AssigneeBioNumerik Pharmaceuticals, Inc.
InventorFrederick H. Hausheer
Life of this patent
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Abstract
This invention relates to a method of treating patients at risk of developing a free radical induced malignancy. The method includes administering an effective amount of a thiol or reducible disulfide compound according to the formula set forth in the specification to a patient at risk.
Claims4
A method of reducing the risk of a patient developing a free radical induced malignancy, said method comprising administering an effective amount of a compound of formula I:
- ##STR4## wherein:
- R.sub.1 is lower alkyl or ##STR5## R.sub.2 and R.sub.4 are each individually SO.sub.3.sup.- M.sup.+, PO.sub.3.sup.2- M.sub.2.sup.2+, or PO.sub.2 S.sup.2- M.sub.2.sup.2+ ;
- R.sub.3 and R.sub.5 are each individually hydrogen, hydroxy or sulfhydryl;
- m and n are individually 0, 1, 2, 3 or 4, with the proviso that if m or n is 0, then R.sub.3 is hydrogen;
- and
- M is hydrogen or an alkali metal ion;
- or
- a pharmaceutically acceptable salt thereof.
5 more elements
Dependencies are inferred from the claim text.