Method for preventing or arresting liver damage in humans
OwnerRan Oreninventor
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Abstract
The invention provides methods for treating liver disease by inducing a hypothyroid state using (i) drugs, e.g., PTU, methimazole, lithium or carbimazole; (ii) surgery; or, (iii) radiation, e.g., .sup.127 I or .sup.131 I. The liver diseases that can be treated using the methods of the invention include: infectious hepatitis, such as (i) viral hepatitis resulting from infection with hepatitis A, D, C, D, E, or G; or (ii) parasitic hepatitis resulting from infection with Schistosoma mansoni, Schistosoma hematobium or Schistosoma japonicum; or (iii) autoimmune disease, e.g., (a) autoimmune hepatitis or (b) primary biliary cirrhosis.
Claims20
A method for treating liver damage associated with infection or autoimmune disease in a patient comprising inducing in a patient afflicted with said infection or autoimmune disease and in need of such treatment by administering a therapeutically effective amount of propylthiouracil in quantities to effect a biochemical hypothyroid condition and maintaining said condition for the duration of the treatment of said patient.
A method for and treating liver damage associated with T-cell mediated disease in a patient comprising inducing in a patient afflicted with said T-cell mediated disease and in need of such treatment by administering a therapeutically effective amount of propylthiouracil in quantities to effect a biochemical hypothyroid condition and maintaining said condition for at least three months.
A method for treating liver damage associated with infectious disease in a patient comprising inducing in a patient afflicted with said infectious disease and in need of such treatment by administering a therapeutically effective amount of propylthiouracil in quantities to effect a biochemical hypothyroid condition and maintaining said condition at least three months.
Dependencies are inferred from the claim text.