Quinoxalinedione derivatives, their production and use in pharmaceutical agents

Compounds of formula I ##STR5## in which R.sup.1 means --(CH.sub.2).sub.n --CR.sup.2 H--(CH.sub.2).sub.m --Z and

• R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are the same or different and mean hydrogen, C.sub.1-6 alkyl, CF.sub.3, nitro, halogen, cyano, SO.sub.p R.sup.11, SO.sub.2 NR.sup.12 R.sup.13, SO.sub.3 H, SO.sub.3 C.sub.1-6 alkyl, OR.sup.14, phenyl, pyridyl or
• substituted phenyl having a substituent selected from the group consisting of C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, nitro, trifluoromethyl, NR.sup.15 R.sup.16, and SR.sup.14, whereby
• R.sup.2 means hydrogen or --(CH.sub.2).sub.q --R.sup.3,
• R.sup.3 means hydrogen, hydroxy, C.sub.1-6 alkoxy or NR.sup.5 R.sup.16,
• n, m and q each mean 0, 1, 2 or 3,
• Z means POXY, OPOXY, SO.sub.2 R.sup.17, CO.sub.2 R.sup.18, cyano or tetrazole,
• R.sup.11 means H, C.sub.1-6 alkyl, phenyl,
• p means 0, 1 or 2,
• R.sup.12, R.sup.13 and R.sup.18 mean hydrogen or C.sub.1-4 alkyl,
• R.sup.14 means H, unsubstituted C.sub.1-6 alkyl or C.sub.1-6 alkyl substituted in 1-3 places with halogen,
• R.sup.17 means hydroxy, C.sub.1-6 alkoxy or NR.sup.19 R.sup.20,
• X and Y are the same or different and mean hydroxy, C.sub.1-6 alkoxy, C.sub.1-4 alkyl or NR.sup.21 R.sup.22,
• R.sup.15 and R.sup.16 are the same or different and mean hydrogen, C.sub.1-4 alkyl or aryl,
• R.sup.21 and R.sup.22 are the same or different and mean hydrogen, C.sub.1-4 alkyl or aryl,
• R.sup.19 and R.sup.20 are the same or different and mean hydrogen or C.sub.1-4 alkyl,
• as well as their isomers or salts, wherein
• a) at least one of substituents R.sup.5, R.sup.6, R.sup.7 or R.sup.8 is phenyl or pyridyl which is not linked to the quinoxaline moiety via a nitrogen atom and
• b) Z is not CO.sub.2 R.sup.18 where R.sup.5, R.sup.6, R.sup.7 or R.sup.8 is phenyl.