Molecules of the HKID-1-related protein family and uses thereof
AssigneeMillennium Pharmaceuticals, Inc.
InventorRosana Kapeller
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Abstract
Novel HKID-1 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length HKID-1 proteins, the invention further provides isolated HKID-1 fusion proteins, antigenic peptides and anti-HKID-1 antibodies. The invention also provides HKID-1 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an HKID-1 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Claims8
An isolated nucleic acid molecule having a nucleotide sequence selected from the group consisting of:
- (a) The nucleotide sequence shown in SEQ ID NO:
- 1;
- (b) A nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:2;
- and
- (c) A nucleotide sequence complementary to either of the nucleotide sequences in (a) or (b).
Dependencies are inferred from the claim text.