Human endothelin-bombesin receptor

An isolated protein molecule comprising an amino acid sequence selected from the group consisting of:

• (a) at least 30 contiguous amino acids as set forth in SEQ ID NO:2 or encoded by the human cDNA contained in ATCC Deposit No. 75823;
• (b) an amino acid sequence encoded by at least 30 contiguous nucleotides of the coding region of SEQ ID NO:1;
• (c) a protein fragment of the amino acid sequence of SEQ ID NO:2, wherein said fragment binds endothelin;
• (d) a protein fragment encoded by the human cDNA contained in ATCC Deposit No. 75823, wherein said fragment binds endothelin;
• (e) a protein fragment of the amino acid sequence of SEQ ID NO:2, wherein said fragment binds bombesin;
• and
• (f) a protein fragment encoded by the human cDNA contained in ATCC Deposit No. 75823, wherein said fragment binds bombesin.

An isolated protein molecule comprising an amino acid sequence selected from the group consisting of:

• (a) amino acids +9 to +18 of SEQ ID NO:2;
• (b) amino acids +22 to +51 of SEQ ID NO:2;
• (c) amino acids +64 to +92 of SEQ ID NO:2;
• (d) amino acids +94 to +114 of SEQ ID NO:2;
• (e) amino acids +122 to +132 of SEQ ID NO:2;
• (f) amino acids +136 to +145 of SEQ ID NO:2;
• (g) amino acids +155 to +176 of SEQ ID NO:2;
• (h) amino acids +188 to +225 of SEQ ID NO:2;
• (i) amino acids +376 to +394 of SEQ ID NO:2;
• (j) amino acids +397 to +403 of SEQ ID NO:2;
• (k) amino acids +441 to +466 of SEQ ID NO:2;
• (l) amino acids +528 to +536 of SEQ ID NO:2;
• (m) amino acids +538 to +563 of SEQ ID NO:2;
• and
• (n) amino acids +571 to +578 of SEQ ID NO:2.