Oral pharmaceutical preparation containing ibandronat
AssigneeRoche Diagnostics GmbH
InventorsJorn Mockel, Rolf-Dieter Gabel, Heinrich Woog
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Abstract
The invention is directed to well-tolerated pharmaceutical compositions for oral application, containing ibandronate or a physiologically tolerable salt thereof as active substance, the administration form consisting of an active substance-containing inner portion enclosed in such fashion by a coat free of active substance that rapid release of the active substance takes place.
Claims3
A method of treating a bone disease in a patient in need thereof, comprising orally administering to the patient a pharmaceutical formulation comprising a tablet core containing about 0.1 to 100 mg of ibandronate and a coating which is free of ibandronate and has the following proportional composition:
- (a) about 51.425% by weight of methylhydroxypropylcellulose;
- (b) about 24.650% by weight of titanium dioxide;
- (c) about 15.000% by weight of polyethylene glycol;
- and
- (d) about 8.925% by weight of talc.
Dependencies are inferred from the claim text.