Back to results
US 6,136,029 AGranted
Bone substitute materials
AssigneePhillips-Origen Ceramic Technology, LLC
InventorsWesley D. Johnson, James R. Johnson, Jeffrey G. Marx
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneePhillips-Origen Ceramic Technology, LLC
InventorsWesley D. Johnson, James R. Johnson, Jeffrey G. Marx
Estimating the term…
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume and having open interconnecting interstices extending throughout said volume and opening through said surface. The article comprises a continuous strong framework structure having interstices which interconnect throughout the bulk volume and a second continuous material occupying at least a portion of the same bulk volume as the framework structure. The second material comprises an osteoinductive and/or osteoconductive composition. This composition may be present in one of several forms. One of these is as a coating on the surface of the framework structure. A second form is in the form of a composite, intimately mixed with the framework material within the framework struts. The third form is as a porous mass within the interstices of the framework structure, having pores which are interconnecting with themselves, and with the interstices of the framework structure. Desirably, the porous osteoinductive or osteoconductive composition extends throughout said bulk volume. In a preferred embodiment, the framework structure is formed of a ceramic material. In a further embodiment, the framework structure may be further structurally reinforced with a dense material component integrally affixed thereto.
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume, the article comprising a continuous strong supportive sintered, load-bearing framework having struts defining a plurality of interconnecting interstices throughout the bulk volume, and a porous osteoconductive composition carried by said supporting framework, said article having interconnecting openings extending throughout said volume and opening through said surface with said osteoconductive composition being exposed to said interconnected openings.
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume, the article comprising a continuous strong supportive sintered, load-bearing framework comprising zirconia, the framework having struts defining a plurality of interconnecting interstices throughout the bulk volume, and a porous osteoconductive composition carried by said supporting framework, said article having interconnecting openings extending throughout said volume and opening through said surface with said osteoconductive composition being exposed to said interconnecting openings.
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume and having interconnecting openings extending throughout said volume and opening through said surface, the article comprising a continuous strong supportive sintered, load-bearing framework having struts defining a plurality of interconnecting interstices throughout the bulk volume, a first porous osteoconductive composition carried by said supporting framework, and a second porous osteoconductive composition carried by said first porous osteoconductive composition and exposed to said interconnected openings.
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume and having interconnecting openings extending throughout said volume and opening through said surface, the article comprising a continuous strong supportive sintered, load-bearing framework comprising zirconia, the struts defining a plurality of interconnecting interstices throughout the bulk volume, a first porous osteoconductive composition including hydroxy appetite carried by the supportive framework, and a second porous osteoconductive composition carried by said first composition and exposed to said interconnecting openings, said second composition containing hydroxy appetite in a concentration greater than that of the first composition.
Dependencies are inferred from the claim text.