Allelic polygene diagnosis of reward deficiency syndrome and treatment

A composition comprising

• a) an opiate destruction-inhibiting amount of at least one substance which inhibits the enzymatic destruction of a neuropeptidyl opiate, said substance being selected from the group consisting of amino acids, peptides, and analogues or derivatives of amino acids or peptides;
• b) a neurotransmitter synthesis-promoting amount of at least one neurotransmitter precursor selected from the group consisting of the dopamine precursors L-Tyr, L-Phe and L-dopa, the serotonin precursors L-Trp and 5-hydroxytryptophan, and the gamma amino butyric acid (GABA) precursors L-glutamine, L-glutamic acid, and L-glutamate;
• c) a trytophan concentration enhancing amount of a mineral compound selected from the group consisting of chromium picolinate and chromium nicotinate;
• and
• d) an amount of at least one substance selected from the group consisting of a Rhodiola extract and huperzine the amounts of said substances, said neurotransmitter precursor, said mineral compound and said Rhodiola extract or huperzine being chosen so that the composition is effective in reducing Attention Deficits disorder with or without hyperactivity.