GABA and L-glutamic acid analogs for antiseizure treatment
AssigneesNorthwestern University, Warner-Lambert Company
InventorsRichard B. Silverman, Ryszard Andruszkiewicz, Po-Wai Yuen, Denis Martin Sobieray, Lloyd Charles Franklin, Mark Alan Schwindt
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Abstract
A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
Claims1
A method for treating anxiety in a mammal in need of treatment comprising administering and antianxiety effective amount of S-(+)4-amino-3-(2-methylpropyl) butanoic acid.
Dependencies are inferred from the claim text.