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AssigneeHSC Research and Development Limited Partnership
InventorsDerek van der Kooy, Roderick McInnes, Bernard Chiasson, Vincenzo Tropepe
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The invention relates to stem cells isolated from the retina of mammals and retinal cells differentiated from these stem cells. The invention also relates to a method of isolating retinal stem cells and inducing retinal stem cells to produce retinal cells. Retinal stem cells may also be induced in vivo to produce retinal cells. The invention also includes pharmaceuticals made with retinal stem cells or retinal cells which may be used to restore vision lost due to diseases, disorders or abnormal physical states of the retina. The invention includes retinal stem cell and retinal cell culture systems for toxicological assays, for isolating genes involved in retinal differentiation or for developing tumor cell lines.
Retinal stem cells isolated from the retina of a mammal.
A method for obtaining cells from a retinal pigment epithelial layer of a mammal, comprising:
A method of preparing progenitor cells or progenitor cells and retinal cells, comprising administering a growth factor and/or a trophic factor to a retinal stem cell so that the retinal stem cell produces progenitor cells, or progenitor cells and retinal cells.
Dependencies are inferred from the claim text.