US 6,117,657 AGranted

Non-nucleotide containing enzymatic nucleic acid

AssigneeRibozyme Pharmaceuticals, Inc.

InventorsNassim Usman, Francine Wincott, Jasenka Matulic-Adamic, Leonid Beigelman, Alex Karpeisky

Life of this patent

Estimating the term…

Abstract

Enzymatic nucleic acid molecule containing one or more non-nucleotide mimetics, and having activity to cleave an RNA or DNA molecule.

Claims13

Dependent claims

A nucleic acid molecule comprising an abasic moiety at the 3' end or at the 5' end or at both the 3' end and the 5' end of said nucleic acid molecule, wherein said abasic moiety lacks a nucleic acid base.

Dependencies are inferred from the claim text.

Facts

Application: 09/182,975Filed 29 Oct 1998 · continuation
Priority: 2 Sep 1993
Granted: 12 Sep 2000
Term ends: Not estimatedThe source records don’t support an estimate.

Classification23 codes

C07H 21/00
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate
C07H 19/06
Heterocyclic radicals containing only nitrogen atoms as ring hetero atom: pyrimidine radicals
C07H 19/10
Pyrimidine radicals: with the saccharide radical esterified by phosphoric or polyphosphoric acids
C07H 19/16
Heterocyclic radicals containing only nitrogen atoms as ring hetero atom: purine radicals

Family

Serial116,177Parent of this continuation-in-part · filed 2 Sep 1993
Serial152,481Parent of this continuation-in-part · filed 12 Nov 1993
Serial233,748Parent of this continuation-in-part · filed 19 Apr 1994
Serial363,253Parent of this continuation · filed 23 Dec 1994
US 5,891,683 AParent of this continuation
US 6,117,657 AThis patent

From the US filing history. Foreign family members aren’t listed.

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