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US 6,117,445 AGranted
Methods for the prevention and treatment of fibrosis and sclerosis
AssigneeLink Technology Incorporated
InventorConstance F. Neely
Life of this patent
Estimating the term…
Abstract
Methods of treating or preventing fibrosis and sclerosis by the administration of compositions containing A.sub.1 adenosine receptor antagonists and/or P.sub.2X purinoceptor antagonists, or combinations thereof.
Claims23
A method of treating a disorder that results in fibrosis or sclerosis, in a subject in need of such treatment, comprising administering to said subject a composition selected from the group consisting of:
- (a) A.sub.1 adenosine receptor antagonists;
- (b) P.sub.2X purinoceptor antagonists;
- and
- (c) a combination of at least one A.sub.1 adenosine receptor antagonist and at least one P.sub.2X purinoceptor antagonist;
- wherein said composition is administered in an amount effective to reduce the rate of fibrosis or sclerosis.
2 more elements
A method of preventing fibrosis or sclerosis in a subject in need of such treatment, comprising administering to said subject a composition selected from the group consisting of:
- (a) A.sub.1 adenosine receptor antagonists;
- (b) P.sub.2X purinoceptor antagonists;
- and
- (c) a combination of at least one A.sub.1 adenosine receptor antagonist and at least one P.sub.2X purinoceptor antagonist;
- wherein said composition is administered in an amount effective to reduce the formation of fibrotic or sclerotic tissue that would occur in the absence of such treatment.
2 more elements
Dependencies are inferred from the claim text.