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US 6,110,484 AGranted
Collagen-polymer matrices with differential biodegradability
AssigneeCohesion Technologies, Inc.
InventorDavid H. Sierra
Life of this patent
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Abstract
The current invention is a biomedical implant comprising a biomedical matrix material and a biodegradable porosifying agent. As the porosifying agent degrades in situ, an implant with an inter-connecting network is formed. The resultant mechanically stable implant allows for tissue and fluid influx into the matrix. The invention is also directed to a method for repair of mammalian tissue using the above-described implant.
Claims1
A method for forming a fibrin matrix at a tissue site comprising the steps of:
- providing particulate crosslinked gelatin in dry, liquid or solid form;
- mixing an effective fibrin-forming amount of thrombin with the particulate crosslinked gelatin to form a mixture;
- and
- allowing the mixture to further mix with fibrinogen at the tissue site.
1 more element
Dependencies are inferred from the claim text.