Loading patent…
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsTimothy R. Billiar, Edith Tzeng, Larry L. Shears, II, David A. Geller, Howard David James Edington
Estimating the term…
The present invention provides a method of promoting the closure of a wound in a patient. This method involves transferring exogenous iNOS to the region of the wound whereby a product of iNOS is produced in the region of the wound to promote the closure of the wound. The present invention also provides a method of transplanting a graft into a patient, which method involves transferring a vector comprising an iNOS expression cassette to cells associated with the graft and surgically incorporating the graft tissue into the patient. Upon expression of iNOS within the patient, a product of iNOS is produced in the region of the graft to attenuate vasculopathy in the region of the graft.
A method of promoting the closure of a wound in a patient which comprises transferring exogenous iNOS to the region of said wound by transferring to cells associated with said wound a vector comprising an iNOS expression cassette, such that iNOS is produced in said cells, whereby a product of iNOS is produced in the region of said wound to promote the closure of said wound.
A method of transplanting a graft into a patient comprising:
Dependencies are inferred from the claim text.