Method for predicting the presence of congenital and therapeutic conditions from coagulation screening assays

A method for predicting the presence of at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis or hemostasis from at least one time-dependent measurement profile, comprising;

• a) adding one or more reagents to a sample to cause coagulation in said sample and performing at least one time-dependent measurement on said sample by taking a plurality of measurements of a property of said sample over time, which property changes when said sample undergoes coagulation, so as to derive a respective at least one time-dependent measurement profile;
• b) defining a set of a plurality of predictor variables which define the at least one time-dependent measurement profile;
• c) deriving a model that represents the relationship between the at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis or hemostasis, and the set of predictor variables;
• and
• d) utilizing the model of step c) to predict the presence of the at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis or hemostasis in the sample.