Human cyclic nucleotide PDEs
AssigneeIncyte Pharmaceuticals, Inc.
InventorsStephen C. Phillips, Jeremy Lanfear, Lindsay Fawcett, Olga Bandman
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Abstract
The invention provides human cyclic nucleotide phosphodiesterases (HSPDE10A) and polynucleotides which identify and encode HSPDE10A. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPDE10A.
Claims15
An isolated and purified polynucleotide encoding the polypeptide comprising the amino acid sequence of SEQ ID NO:
- 1 or SEQ ID NO:
- 3 or a fragment thereof.
An isolated and purified polynucleotide comprising the polynucleotide sequence of SEQ ID NO:2, SEQ ID NO:4, a fragment of SEQ ID NO:2 having enzymatic activity, or a fragment of SEQ ID NO:4 having enzymatic activity.
Dependencies are inferred from the claim text.