Antiallergic compostion
AssigneesChisei RA, Yoshitomi Pharmaceuticals Industries, Ltd.
InventorsChisei Ra, Koji Naito, Minoru Hirama, Ko Okumura
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Abstract
Disclosed is an antiallergic composition comprising, as an active ingredient, a peptide which is capable of binding to human IgE, more specifically the high-affinity immunoglobulin E receptor .alpha. chain or a soluble fragment, which is capable of binding to human IgE, or the high-affinity immunoglobulin E receptor .alpha. chain. The composition is clinically useful for blocking allergic responses.
Claims7
A method of preventing an allergic response selected from the group consisting of anaphylactic shock, pollen allergy, atopic dermatitis and bronchial asthma in a human, which method comprises, administering to said human prior to onset of said allergic response and prior to a stage where IgE concentration is elevated, an antiallergic composition which comprises, as an active ingredient, a peptide having a portion of an amino acid sequence of SEO ID NO. 1, said peptide being capable of binding to human IgE and which contains a soluble IgE binding fragment of a high affinity immunoglobulin E receptor .alpha.-chain of human origin.
Dependencies are inferred from the claim text.