Reagentless analysis of biological samples
AssigneeAbbott Laboratories
InventorsTzyy-Wen Jeng, Larry L. McDowell, Joseph Larry Pezzaniti, Gary M. Oosta, Eric B. Shain
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AssigneeAbbott Laboratories
InventorsTzyy-Wen Jeng, Larry L. McDowell, Joseph Larry Pezzaniti, Gary M. Oosta, Eric B. Shain
Estimating the term…
Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e.g, urine. A biological sample particularly suitable for the apparatus and method of this invention is urine. In general, spectroscopic measurements can be used to quantify the concentrations of one or more analytes in a biological sample. In order to obtain concentration values of certain analytes, such as hemoglobin and bilirubin, visible light absorption spectroscopy can be used. In order to obtain concentration values of other analytes, such as urea, creatinine, glucose, ketones, and protein, infrared light absorption spectroscopy can be used. The apparatus and method of this invention utilize one or more mathematical techniques to improve the accuracy of measurement of parameters of analytes in a biological sample. The invention also provides an apparatus and method for measuring the refractive index of a sample of biological fluid while making spectroscopic measurements substantially simultaneously.
A method for determining concentration of at least one analyte of interest in a liquid biological sample from an individual by means of spectroscopic analysis, said method comprising the steps of:
Dependencies are inferred from the claim text.