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AssigneeNew York Blood Center, Inc.
InventorsHenrietta Margolis-Nunno, Ehud Ben-Hur, Bernard Horowitz
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The present invention concerns a process for inactivating extracellular and intracellular virus in a biological composition without incurring substantial disruption or inactivation thereof, said process comprising subjecting said composition to a virucidally effective amount of UVA1 irradiation substantially in the absence of UVA2 irradition for a period of time sufficient to thereby inactivate said virus while retaining functionality of said composition. The biological composition is advantageously a product that contains red blood cells or platelets. The process is advantageously carried out in the presence of an irradiation sensitizer compound and/or a quencher. The present invention also concerns the product substantially identical to that produced bythe inventive process.
A process for treating a biological composition to inactivate an extracellular or intracellular virus that may be present therein, said process comprising performing two viral inactivation methods on said biological composition, wherein one of said two methods comprises the steps of:
Dependencies are inferred from the claim text.