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US 6,074,661 AGranted
Sterile bioerodible occular implant device with a retinoid for improved biocompatability
AssigneeAllergan Sales, Inc.
InventorsOrest Olejnik, Patrick M. Hughes, John S. Kent
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Abstract
An implantable device is provided which incorporates a retinoid for improving the biocompatability of the device in eye tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a permanent implant which includes a surface treated with a retinoid for increasing the biocompatibility thereof.
Claims3
A method for improving biocompatability of an implantable controlled release therapeutic delivery device in eye tissue, the method comprising the steps of:
- incorporating a therapeutic agent into said device in a manner enabling controlled release of said therapeutic agent;
- and
- incorporating a retinoid into said device in an amount effective for improving biocompatability of said device in said eye tissue;
- said therapeutic agent and retinoid being homogeneously distributed throughout said device, said retinoid being incorporated in an amount between about 0.001% and about 50% of said therapeutic agent.
1 more element
Dependencies are inferred from the claim text.