Cleaning-in-place with a solution containing a protease and a lipase

A method of cleaning-in-place process equipment soiled with a material containing fats and proteins comprising contacting a surface of the equipment soiled with fats and proteins with a solution consisting essentially of a 0.00001% to 0.1% of a protease enzyme calculated as pure enzyme protein, and 0.00001% to 0.1% of a lipase enzyme calculated as pure enzyme protein, for a sufficient period of time to substantially remove the soiled fat and protein material.