Application of botulinum toxin to the management of neurogenic inflammatory disorders
OwnerEric R. Firstinventor
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Abstract
The present invention provides a method for the use of at least one serotype or a combination of serotypes of Botulinum neurotoxin either alone or in combination with other peptides or fusion proteins, that when administered in a safe and effective amount, antagonize and therefore decrease or block inflammation induced by the neurogenic mechanisms underlying or associated with inflammatory disorders, in particular, arthritis.
Claims6
A method for treating neurogenic inflammation comprising, administering a therapeutically effective amount of Clostridium botulinum toxin to antagonize the action of at least one neurogenic inflammatory mediator, whereby said toxin interrupts a neurogenic pathway associated with said neurogenic inflammation.
Dependencies are inferred from the claim text.