Optical diffraction biosensor
AssigneeKimberly-Clark Worldwide, Inc.
InventorsDennis S. Everhart, Mark L. Jones, Rosann Marie Kaylor
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Abstract
The present invention provides an inexpensive and sensitive device and method for detecting and quantifying analytes present in a medium. The device comprises a metalized film upon which is printed a specific, predetermined pattern of analyte-specific receptors. Upon attachment of a target analyte to select areas of the plastic film upon which the receptor is printed, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.
Claims29
A biosensor comprising:
- a polymer film coated with metal;
- and
- a patterned receptor layer printed onto the polymer film wherein the receptor layer has a receptive material thereon that specifically binds an analyte;
- wherein the receptor layer is printed in a pattern such that when the biosensor binds an analyte, the biosensor diffracts transmitted light or reflected light to form a diffraction pattern visible to an unaided eye.
A method of making a biosensor comprising applying a receptor layer to a polymer film coated with metal in a pattern such that when an analyte binds to the patterned receptor layer, the patterned receptor layer thereby forms a diffraction image visible to an unaided eye.
Dependencies are inferred from the claim text.