US 6,057,439 AGranted

Steroids as neurochemical stimulators of the VNO to alleviate symptoms of PMS and anxiety

AssigneePherin Corporation

InventorsClive L. Jennings-White, David L. Berliner, Nathan W. Adams, Luis Monti-Bloch

Life of this patent

Estimating the term…

Abstract

The invention relates to a method of alleviating the symptoms of PMS and anxiety. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers.

Claims12

Dependent claims

The steroid 16.alpha.,17.alpha.-epoxyestr-4-en-10.beta.-ol-3-one.

Dependencies are inferred from the claim text.

Facts

Application: 08/686,092Filed 23 Jul 1996 · continuation in part
Priority: 4 Aug 1994
Granted: 2 May 2000
Term ends: Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61K 31/573
Substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone: substituted in position 21, e.g. cortisone,…
A61K 31/568
Not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol: substituted in positions 10 and 13 by a chain having at least one…
A61K 31/57
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids: substituted in position 17 beta by a chain…
C07J 3/00
Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17

Family

Serial286,073Parent of this continuation-in-part · filed 4 Aug 1994
Serial625,268Parent of this continuation-in-part · filed 29 Mar 1996
US 5,563,131 AParent of this continuation-in-part
US 6,057,439 AThis patent

From the US filing history. Foreign family members aren’t listed.

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