Encapsulation device

An empty device for receiving a bioactive agent, comprising:

• a biocompatible and semi-permeable membrane having an inner surface and an outer surface, wherein said inner surface defines an enclosed space;
• said membrane also having one end that defines an opening for introducing the bioactive agent into said enclosed space;
• and
• a biocompatible adhesive in the general region of said opening to allow sealing of said opening after the introduction of the bioactive agent into said enclosed space, wherein said biocompatible adhesive is a heat sealable polymer conduit extending beyond said end of said membrane for a length sufficient to allow heat sealing of said conduit without causing said membrane to be contacted with a heated element in the heat sealing process;
• said conduit overlapping and being secured to a terminal portion of the outer surface of said membrane,
• wherein said device is configured to be placed in an animal and said membrane is in the form of a preformed bag.