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US 6,040,193 AGranted
Combinatorial strategies for polymer synthesis
AssigneeAffymetrix, Inc.
InventorsJames L. Winkler, Stephen P. A. Fodor, Christopher J. Buchko, Debra A. Ross, Lois Aldwin, Douglas N. Modlin
Life of this patent
Estimating the term…
Abstract
An array is created by moving a dispenser toward a solid support until a tip of the dispenser touches the support, withdrawing the tip from the surface and releasing a drop of 5 nanoliters or less in an area smaller than 1 mm.sup.2 to create an array of at least 100 spots.
Claims14
A method of forming an array of polymers on a solid support, comprising:
- (a) moving a dispenser containing a solution of a polymer toward a surface of a solid support until a tip of the dispenser touches the surface, moving the dispenser away from the surface and releasing a droplet of 5 nl or less from the dispenser, the droplet contacting the surface at a localized area smaller than 1 mm.sup.2, whereby the polymer attaches to the surface of the support at the localized area;
- (b) repeating (a) to attach a different polymer at a different localized area until an array of at least 100 different polymers at different localized areas is formed.
Dependencies are inferred from the claim text.