Proteinase inhibitor, precursor thereof and genetic sequences encoding same
AssigneeThe University of Melbourne
InventorsMarilyn Anne Anderson, Angela Hilary Atkinson, Robyn Louise Heath, Adrienne Elizabeth Clarke
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Abstract
The present invention relates generally to proteinase inhibitors, a precursor thereof and to genetic sequences encoding same. More particularly, the present invention relates to a nucleic acid molecule comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein said precursor comprises at least three PI monomers and wherein at least one of said monomers has a chymotrypsin specific site and at least one other of said monomers has a trypsin specific site.
Claims7
An isolated nucleic acid comprising a sequence of nucleotides which encodes or is complementary to a sequence which encodes a type II serine proteinase inhibitor (PI) precursor from a plant wherein said isolated nucleic acid has the nucleotide secuence set forth in SEQ ID NO:1 or hybridizes to the nucleotide sequence set forth in SEQ ID NO:1 under the conditions of at least one of 4.times.SSC at room temperature, 2.times.SSC at room temperature, 1.times.SSC at 40.degree. C., 2.times.SSC with 0.1% w/v SDS at 68.degree. C., or 0.2.times.SSC with 1% w/v SDS at 68.degree. C., wherein said precursor comprises at least three PI monomers and wherein at least one of said monomers has a chymotrypsin specific site and at least one of said monomers has a trypsin specific site.
Dependencies are inferred from the claim text.