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US 6,031,080 AGranted
Chemotactic cytokine
AssigneeLudwig Institute for Cancer Research Imperial College of Science, Technology & Medicine
InventorsTimothy J. Williams, Peter J. Jose, David A. Griffiths-Johnson, John J. Hsuan
Life of this patent
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Abstract
A chemoattractant protein called "eotaxin" is capable of attracting eosinophils and of inducing eosinophil accumulation and/or activation in vitro and in vivo. Various types of agents that inhibit or otherwise hinder the production, release or activity of eotaxin may be used therapeutically in the treatment of asthma and other inflammatory diseases.
Claims1
A substantially purified chemoattractant polypeptide from the C--C chemokine family consisting of the amino acid sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.