Implantable radiotherapy device
AssigneeRadioMed Corporation
InventorsPiran Sioshansi, Raymond J. Bricault
Life of this patent
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Abstract
A general purpose implantable radiotherapy device for delivering a predetermined dose of radiation in a predetermined radiation pattern. The device includes a biocompatible template adapted for implantation at a treatment site in a patient, and one or more radiation sources which are incorporated directly into at least a portion of the template, preferably by ion implantation methods. The shape of the radiation pattern from the device is determined at least in part by the location and distribution of the radiation source or sources incorporated into the template, and not solely by the shape of the template. The device is suitable for a wide variety of radiotherapy applications.
Claims55
A general purpose radiotherapy device for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, said device comprising:
- a. a template made of a biocompatible material and adapted for implantation into or near a localized lesion or tumor in a patient;
- and
- b. at least one source of radiation incorporated into at least a portion of the template to render said portion of the template radioactive and define a unitary, structurally non-supporting radiation delivery device,
- wherein the shape of said radiation pattern is determined at least in part by the distribution of said source of radiation on the exterior surfaces of said template and is not determined solely by the shape of the template.
A general purpose radiotherapy device for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, said device comprising:
- a. a template made of a biocompatible material and adapted for implantation at a treatment site in a patient;
- and
- b. at least one source of radiation incorporated into at least a portion of the template to render said portion of the template radioactive,
- wherein the shape of said radiation pattern is determined at least in part by the distribution of said source of radiation on the exterior surfaces of said template and is not determined solely by the shape of the template,
- wherein said template is in the form of a substantially elongated flexible filament which extends along a principal axis, wherein radiation is emitted from said filament in a substantially elongated radiation pattern extending along and radially from said principal axis, and
- wherein said filament is made of a nonmetal.
A general purpose radiotherapy device for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, said device comprising:
- a. a biocompatible flexible filament adapted for implantation into or near a localized lesion or tumor in a patient, wherein the filament is bendable in situ to accommodate various lesion geometries;
- and
- b. at least one source of radiation incorporated into at least a portion of the filament to render said portion of the filament radioactive and define a unitary, structurally non-supporting radiotherapy delivery device.
A general purpose radiotherapy device for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, said device comprising:
- a. a filament made of a biocompatible material and adapted for implantation at or near a treatment site in a patient;
- and
- b. at least one source of radiation incorporated into at least a portion of the filament to render said portion of the filament radioactive, wherein said filament is made of a nonmetal.
A general purpose radiotherapy device for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, said device comprising:
- a. a biocompatible, substantially solid template adapted for implantation into or near a localized lesion or tumor in a patient;
- and
- b. at least one source of radiation incorporated into at least a portion of the template to render said portion of the template radioactive and define a unitary, structurally non-supporting radiotherapy delivery device,
- wherein the shape of said radiation pattern is determined at least in part by the distribution of said source of radiation on the exterior surfaces of said template and is not determined solely by the shape of said template.
A method of treatment of a localized lesion with a predetermined dose of radiation, comprising the steps of:
- a. providing a template made of a biocompatible material and adapted for implantation into or near a localized lesion or tumor in a patient, and at least one source of radiation adapted for incorporation into at least a portion of the template to render said portion of the template radioactive and define a unitary, structurally non-supporting radiotherapy delivery device,
- b. incorporating said radiation source into said template according to a predetermined distribution pattern, whereby the shape of the pattern of radiation provided by said device is determined at least in part by the distribution of said source of radiation on the exterior surfaces of said template and is not determined solely by the shape of said template;
- and
- c. implanting the device into or near a localized lesion or tumor in a patient.
A kit for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, the kit comprising:
- a. a general purpose radiotherapy device, including a flexible filament made of a biocompatible material and adapted for implantation into or near a localized lesion or tumor in a patient, and at least one source of radiation incorporated into at least a portion of the filament to render said portion of the filament radioactive and define a unitary, structurally non-supporting radiotherapy delivery device, wherein the shape of said radiation pattern is determined at least in part by the distribution of said source of radiation on the exterior surfaces of said filament and is not determined solely by the shape of said filament, wherein the filament is bendable in situ to accommodate various lesion geometries;
- and
- b. a syringe for implanting the device into the patient.
A general purpose radiotherapy device for delivering to a treatment site in a patient a predetermined dose of radiation in a predetermined radiation pattern, said device comprising:
- a. a template made of a biocompatible material and adapted for implantation at a treatment site in a patient;
- and
- b. at least one source of radiation incorporated into at least a portion of the template to render said portion of the template radioactive,
- wherein the shape of said radiation pattern is determined at least in part by the distribution of said source of radiation on the exterior surfaces of said template and is not determined solely by the shape of the template,
- wherein said template is made of a nonmetal.
Dependencies are inferred from the claim text.