GABA and L-glutamic acid analogs for antiseizure treatment
AssigneesNorthwestern University, Warner-Lambert Company
InventorsRichard B. Silverman, Ryszard Andruszkiewicz, Po-Wai Yuen, Denis Martin Sobieray, Lloyd Charles Franklin, Mark Alan Schwindt
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Abstract
A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are also disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are further disclosed.
Claims2
A compound which is
- 3-(hydroxymethyl)-5-methyl-hexanoic acid, phenylmethyl ester.
A compound which is
- 3-(hydroxymethyl)-5-methyl-hexanoic acid, 1,1-dimethyl ester.
Dependencies are inferred from the claim text.