DNA coding for a peptide of a papilloma virus main capside protein and use thereof
AssigneeDeutsches Krebsforschungzentrum Stiftung des Offentlichen Rechts
InventorsVladimir Shamanin, Ethel-Michele De Villiers-Zur Hausen, Irene Leigh, Harald Zur Hausen
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Abstract
This invention relates to a DNA encoding a peptide of a papilloma virus major capsid protein. Furthermore, this invention deals with a papilloma virus genome containing such a DNA. In addition, this invention concerns proteins encoded by the papilloma virus genome and virus-like particles as well as antibodies directed thereagainst and the use thereof and the use thereof in diagnosis, treatment and vaccination.
Claims27
An isolated DNA encoding a peptide an L1 papilloma virus major capsid protein, wherein said peptide comprises the amino acid sequence of FIG. 2 (SEQ ID NO:
- 2), FIG. 3 (SEQ ID NO:
- 3), FIG. 4 (SEQ ID NO:
- 4) FIG. 5 (SEQ ID NO:
- 5), FIG. 6 (SEQ ID NO:
- 6), FIG. 7 (SEQ ID NO:
- 7), FIG. 8 (SEQ ID NO:
- 8), or FIG. 9 (SEQ ID NO:
- 9).
An isolated DNA encoding an L1 papilloma virus major capsid protein, wherein said L1 polypeptide comprises the amino acid sequence of FIG. 1 (SEQ ID NO:
- 1), FIG. 2 (SEQ ID NO:
- 2), FIG. 3 (SEQ ID NO:
- 3), FIG. 4 (SEQ ID NO:
- 4), FIG. 5 (SEQ ID NO:
- 5), FIG. 6 (SEQ ID NO:
- 6), FIG. 7 (SEQ ID NO:
- 7), FIG. 8 (SEQ ID NO:
- 8), or FIG. 9 (SEQ ID NO:
- 9).
Dependencies are inferred from the claim text.