Dispersible antibody compositions and methods for their preparation and use
AssigneeInhale Therapeutic Systems
InventorsRobert M. Platz, John S. Patton, Linda C. Foster, Mohammed Eljamal
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Abstract
This invention relates to dispersible antibody compositions and methods for preparing and using these compositions. In particular, the present invention relates to dry powder dispersible antibody compositions wherein antibody conformation is preserved. The compositions have good powder dispersibility and other desirable characteristics for pulmonary delivery of therapeutic antibodies.
Claims13
An IgG antibody-based dry powder composition for pulmonary delivery comprising a predetermined amount of IgG antibody which is non-aggregated and is in its native conformation in respirable dry powder particles having a particle size less than 10 micrometers wherein said composition has a delivered dose efficiency of at least about 30%.
Dependencies are inferred from the claim text.