Feline leukemia virus vaccines
OwnerRichard C. Wardley, Darrell R. Thomseninventors
Life of this patent
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Abstract
Disclosed are recombinant baculovirus expressing the gag, gp70, and gp85 genes of feline leukemia virus. Also disclosed are vaccines based on protein expressed from these recombinants. Also disclosed is a combined mucosal/parenteral inoculation method.
Claims20
A multiple dose FeLV vaccination kit for a cat comprising:
- (a) a dose for parenteral administration comprising baculovirus expressed FeLV gp85 protein;
- and
- (b) a dose for mucosal administration comprising recombinant FHV engineered to express the DNA coding for the FeLV gp85.
A multiple dose FeLV vaccination kit for a cat comprising:
- (a) a dose for parenteral administration comprising baculovirus expressed FeLV gp85 and gag protein;
- and
- (b) a dose for mucosal administration comprising recombinant FHV engineered to express the DNA coding for the FeLV gp85 and gag genes.
A multiple dose FeLV vaccination kit for a cat comprising:
- (a) a dose for parenteral administration comprising baculovirus expressed FeLV gp85 and gag proteins;
- and
- (b) a dose for parenteral administration comprising baculovirus expressed FeLV gp85 protein, baculovirus expressed FeLV gp70 protein and baculovirus expressed FeLV gag protein.
A multiple dose FeLV vaccination kit for a cat comprising:
- (a) a dose comprising baculovirus expressed FeLV gp70 protein for parenteral administration;
- (b) two separate doses for mucosal administration comprising recombinant FHV engineered to express the DNA coding for the FeLV gp70 gene.
A method of conferring immunity to FeLV to a cat comprising:
- (a) providing a dose of baculovirus expressed FeLV gp85 protein;
- (b) providing a dose of recombinant FHV engineered to express the DNA coding for the FeLV gp85 gene;
- (c) administering said dose of baculovirus expressed FeLV gp85 protein and said dose of recombinant FHV to said cat.
A method of conferring immunity to FeLV to a cat comprising:
- (a) providing a dose of baculovirus expressed FeLV gp85 and gag protein;
- (b) providing a dose of recombinant FHV engineered to express the DNA coding for the FeLV gp85 and gag genes;
- (c) administering said dose of baculovirus expressed FeLV gp85 and gag protein and said dose of recombinant FHV to said cat.
A method of conferring immunity to FeLV to a cat comprising:
- (a) providing a first dose of baculovirus expressed FeLV gp85 and gag protein;
- (b) providing a second dose of baculovirus expressed FeLV gp85, gp70 and gag protein;
- (c) administering said dose of baculovirus expressed FeLV gp85 and gag protein and said dose of baculovirus expressed FeLV gp85, gp70 and gag protein to said cat.
A method of conferring immunity to FeLV to a cat comprising:
- (a) providing a dose of baculovirus expressed FeLV gp70 protein;
- (b) providing a first dose of recombinant FHV engineered to express the DNA coding for the FeLV gp70 gene;
- (c) providing a second dose of recombinant FHV engineered to express the DNA coding for the FeLV gp70 gene;
- (d) administering said dose of baculovirus expressed FeLV gp70 protein and said first and second doses of recombinant FHV to said cat.
Dependencies are inferred from the claim text.