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US 6,007,811 AGranted
Method of producing fibrin sealant from clotting factors in fish blood
AssigneeSea Run Holdings, Inc.
InventorsEvelyn S. Sawyer, Philip J. Sawyer, Jed B. Gorlin, Paul A. Jamney
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Abstract
The present invention is a fibrin sealant and a method for producing a fibrin sealant from fish blood. Whole blood is drawn from the donor fish and centifuged to separate blood cells from plasma. Prothrombin and fibrinogen are extracted from this plasma, and the prothrombin is activated to thrombin. The fibrinogen and thrombin components are then combined as needed to form the fibrin sealant.
Claims18
A method of producing a fibrin sealant, comprising:
- drawing whole blood from donor fish;
- separating plasma from the whole blood;
- extracting fibrinogen from the plasma;
- extracting prothrombin from the plasma;
- activating the prothrombin to thrombin;
- and
- combining the thrombin and the fibrinogen to form the fibrin sealant.
4 more elements
A method of producing a fibrin sealant, comprising:
- drawing whole blood from donor fish;
- separating plasma from the whole blood;
- extracting fibrinogen from the plasma;
- and
- combining mammalian thrombin with the fibrinogen to form the fibrin sealant.
2 more elements
Dependencies are inferred from the claim text.