Retinoid inhibition of expression of VEGF
AssigneeCentre International de Recherches Dermatologiques
InventorsBarbara Vega, Serge Michel, Annie Ladoux, Christian Frelin
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Abstract
The retinoids, in particular the anti-AP-1 retinoids, effectively inhibit the expression of VEGF, and thus are useful for the therapeutic treatment of disease states manifesting an overexpression of VEGF.
Claims7
A method for inhibiting VEGF expression in keratinocytes, comprising administering in a subject in need of such treatment an effective VEGF expression inhibiting amount of at least one retinoid.
A method for inhibiting, the in vitro expression of VEGF comprising adding to an in vitro culture comprising keratinocytes, an amount of at least one retinoid effective to inhibit VEGF expression.
Dependencies are inferred from the claim text.