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US 5,997,848 AGranted
Methods and compositions for pulmonary delivery of insulin
AssigneeInhale Therapeutic Systems
InventorsJohn S. Patton, Linda Foster, Robert M. Platz
Life of this patent
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Abstract
Systemic delivery of insulin to a mammalian host is accomplished by inhalation of a dry powder of insulin. It has been found that dry insulin powders are rapidly absorbed through the alveolar regions of the lungs.
Claims7
A method for delivering insulin into blood circulation of a patient, said method comprising:
- providing from 1 to 4 individual dry powder insulin dosages having from a total weight of from 0.5 mg to 15 mg of insulin;
- dispersing each of the dry powder insulin doses individually into a gas stream to form dry insulin aerosols;
- and
- inhaling each of the dry powder insulin aerosols into an alveolar region of the patient's lungs;
- wherein the dry insulin powder dissolves in a fluid lining of the alveolar region of the lungs and is systemically absorbed into patient blood circulation.
2 more elements
Dependencies are inferred from the claim text.