Method of cancer cell detection
AssigneeApplied Spectral Imaging Ltd.
InventorsDirk C. Soenksen, George McNamara, Yuval Garini, Nir Katzir
Life of this patent
Estimating the term…
Abstract
A method for cancer cell detection including the steps of (a) staining an analyzed sample with at least first and second dyes, the dyes being selected such that the first dye better adheres to normal cells whereas the second dye better adheres to cancer cells; (b) spectrally imaging the sample through an optical device being optically connected to an imaging spectrometer thereby obtaining a spectrum of each pixel of the sample; (c) based on the spectra, evaluating concentrations of the first and second dyes for each of the pixels; and (d) based on the concentrations detecting the presence of cancer cells in the sample.
Claims20
A method of detecting cancer cells comprising the steps of:
- (a) staining an analyzed sample with at least first and second dyes, said dyes being selected such that said first dye better adheres to normal cells whereas said second dye better adheres to cancer cells;
- (b) spectrally imaging said sample through an optical device being optically connected to an imaging spectrometer thereby obtaining a full spectrum of each pixel of said sample;
- (c) based on said spectra, evaluating concentrations of said first and second dyes for each of said pixels;
- and
- (d) based on said concentrations detecting the presence of cancer cells in said sample;
- said step of spectrally imaging said sample through said optical device being optically connected to said imaging spectrometer and obtaining said full spectrum of each pixel of said sample allows said at least first and second dyes to be spectrally overlapping.
Dependencies are inferred from the claim text.