Therapeutic use of water-soluble fullerene derivatives
AssigneeNational Science Council
InventorsLong Y. Chiang, Yih-Loong Lai, Ming-Cheng Tsai, Yuan-Teh Lee, Huei-Chen Huang, Ming-Kuen Lai, Fong-Jou Lu
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Abstract
A method of treating a free radical-related medical condition. The method includes the step of administering to a subject in need of such treatment an effective amount of a compound of the formula F(--X).sub.m wherein F is a fullerene core; each X is independently OH, (CH.sub.2).sub.n --SO.sub.3 H, or a metal salt of (CH.sub.2).sub.n --SO.sub.3.sup.- in which each n is independently 2-50; and m is 2-40.
Claims15
A method of treating a free radical-related medical condition, said method comprising administering to a subject in need thereof an effective amount of a compound of the formula
- F(--X).sub.m
- wherein
- F is a fullerene core;
- each X is independently OH, (CH.sub.2).sub.n --SO.sub.3 H, or a metal salt of (CH.sub.2).sub.n --SO.sub.3.sup.- in which each n is independently 2-50;
- and
- m is 2-40.
A pharmaceutical composition for treating a free radical-related medical condition, said composition comprising an effective amount of a compound of the formula
- F--(X).sub.m
- wherein
- F is a fullerene core;
- each X is independently (CH.sub.2).sub.n --SO.sub.3 H or a metal salt of (CH.sub.2).sub.n --SO.sub.3.sup.- in which each n is independently 2-50;
- and m is 2-40;
- and a pharmaceutically acceptable carrier thereof.
Dependencies are inferred from the claim text.