Back to results
US 5,994,086 AGranted
Method for assessing infertility by binding of mannose to sperm cells
AssigneeNorth Shore University Hospital
InventorSusan Benoff
Life of this patent
Estimating the term…
Abstract
Methods for labeling mannose lectins on the surface of mammalian sperm cells are described, and methods of categorizing and quantifying the numbers of cells exhibiting particular labeling patterns are also provided. These methods provide ways of detecting whether or not a mammalian male patient has mannose lectin-correlated infertility.
Claims9
A method for assessing in vitro sperm fertilization capability, the method comprising the steps of:
- a) obtaining a sperm test sample;
- b) allowing capacitation to occur in the sample;
- c) contacting the sample with a labeled-mannose containing probe;
- and
- d) assessing the in vitro sperm fertilization capability of the test sample by comparing the mannose binding of the test sample to the mannose binding of sperm with in vitro fertilization capability.
2 more elements
Dependencies are inferred from the claim text.