US 5,989,566 A · Stable vaccine compositions for parenteral administration, a method for their use, and a process for their preparation

Abstract

The invention relates to certain stable vaccine compositions comprising a macrocyclic lactone compound, a milbemycin compound, an avermectin compound or mixtures thereof; at least one antigen; a dispersing agent; an adjuvant; a water soluble organic solvent; and saline or water or mixtures thereof. The invention further relates to stable compositions as described above of a macrocyclic lactone compound, a milbemycin compound, an avermectin compound or mixtures thereof, but without an antigen. The invention also relates to a method for preventing or controlling helminthiasis, infection by acarids and arthropod endo-and ectoparasites and bacterial and viral disease in warm-blooded animals by the parenteral administration of compositions of the invention. The invention further relates to a process for the preparation of the invention compositions.

Claims18

Dependent claims

A vaccine composition consisting essentially on a weight to volume basis about 0.05% to 2.5% of a macrolide compound or mixtures of macrolide compounds;

about 0.1% to 6% of a water-soluble organic solvent;
about 1% to 8% of a dispersing agent;
about 10% to 50% of an adjuvant;
at least one antigen;
up to about 0.1% of a preservative;
and saline or water or a mixture thereof.

3 more elements

Dependencies are inferred from the claim text.

Stable vaccine compositions for parenteral administration, a method for their use, and a process for their preparation

Life of this patent

Stable vaccine compositions for parenteral administration, a method for their use, and a process for their preparation

Life of this patent

Abstract

Claims18