Actin-binding polypeptides and nucleic acids encoding the same
AssigneeUniversity of Massachusetts
InventorsElizabeth J. Luna, Kersi N. Pestonjamasp, Robert K. Pope, Julia D. Wulfkuhle
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Abstract
The invention relates to supervillin polypeptides, nucleic acid molecules encoding supervillin, and uses thereof. Supervillin is related to the actin-binding proteins villin and gelsolin.
Claims16
An isolated nucleic acid molecule encoding a supervillin polypeptide which binds actin, said molecule comprising a nucleotide sequence encoding a polypeptide having a sequence that is at least 85% identical to SEQ ID No:2, wherein the percent identity is calculated using the Genetics Computer Group Sequence Analysis Software Package with the default parameters.
An isolated nucleic acid molecule encoding a supervillin polypeptide which binds actin, said molecule comprising a nucleotide sequence encoding a polypeptide having a sequence that is at least 85% identical to the sequence of SEQ ID No:4, wherein the percent identity is calculated using the Genetics Computer Group Sequence Analysis Software Package with the default parameters.
Dependencies are inferred from the claim text.