Inhibition of angiogenesis by sea cucumber fractions
AssigneeCoastside Bio Resources
InventorPeter Donald Collin
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Abstract
The present invention provides inhibition of angiogenesis in a warm-blooded animal by the administration of preparations isolated from the echinoderm sea cucumber (Class Holothuroidea). This preparation is useful as a therapeutic agent against malignant tumors and as a preventive or therapeutic drug against various diseases, such as rheumatoid arthritis, caused by vascular hyperplasia.
Claims40
A method of inhibiting angiogenesis in a warm blooded animal comprising administering an angiogenesis-inhibiting amount of a composition comprising an active ingredient selected from the group consisting of isolated sea cucumber body wall, isolated sea cucumber epithelial layer, isolated sea cucumber flower, combinations thereof and active derivatives thereof.
A method of inhibiting angiogenesis in a warm blooded animal comprising administering an angiogenesis-inhibiting amount of a composition comprising isolated sea cucumber body wall or active derivatives thereof.
A method of inhibiting angiogenesis in a warm blooded animal comprising administering an angiogenesis-inhibiting amount of a composition comprising isolated sea cucumber epithelial layer or active derivatives thereof.
A method of inhibiting angiogenesis in a warm blooded animal comprising administering an angiogenesis-inhibiting amount of a composition comprising isolated sea cucumber flower or active derivatives thereof.
Dependencies are inferred from the claim text.