Acetic acid derivatives
AssigneeHoffmann-La Roche Inc.
InventorsLeo Alig, Paul Hadvary, Marianne Hurzeler Muller, Marcel Muller, Beat Steiner, Thomas Weller
Life of this patent
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Abstract
Acetic acid derivatives of the formula ##STR1## wherein L, M, T and Q have the significance given in the description, can be used for the treatment or prophylaxis of illnesses which are caused by the binding of adhesive proteins to blood platelets and by blood platelet aggregation and cell--cell adhesion, and are manufactured by cleaving protecting groups in the corresponding protected compounds or by converting the cyano group into the amidino group in corresponding nitrites.
Claims8
The compound ethyl (S)-4-[2-[4-[imino-2-(methoxy-ethoxycarbonylamino)-methyl]-benzoylamino]-p ropionyl]-phenoxyacetate.
The compound ethyl (Z)-(R,S)-4-[2-[4-[amino-hydroxyimino-methyl]-benzoylamino]-propionyl]-phe noxyacetate.
The compound tetrahydropyran-4-yl (S)-4-[2-[4-(ethoxycarbonylamino-imino-methyl)-benzoylamino]-propionyl]-ph enoxyacetate.
The compound ethyl (Z)-(R,S)-4-[2-[4-[amino-ethoxycarbonyloximino-methyl]-benzoylamino]-propi onyl]-phenoxyacetate.
The compound ethyl (S)-4-[2-[4-(imino-phenoxycarbonylamino-methyl)-benzoylamino]-propionyl]-p henoxyacetate.
The compound 2-methoxy-ethyl (S)-4-[2-[4-[imino-(2-methoxy-ethoxycarbonylamino)-methyl]-benzoylamino]-p ropionyl]-phenoxyacetate.
The compound ethyl (Z)-(S)-4-[2-[4-(amino-hydroxyimino-methyl)-benzoylamino]-propionyl]-pheno xyacetate.
The compound ethyl (S)-[4-[2-[4-[(2-acetoxy-ethoxy-carbonylimino)-amino-methyl]-benzoylamino] -propionyl]-phenoxy]-acetate.
Dependencies are inferred from the claim text.