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US 5,973,138 AGranted
Method for purification and manipulation of nucleic acids using paramagnetic particles
AssigneeBecton, Dickinson and Company
InventorMatthew P. Collis
Life of this patent
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Abstract
The present invention relates to a composition which is useful for the reversible binding of a nucleic acid molecule. The composition, which may be packaged in a kit, includes a paramagnetic particle in an acidic solution.
Claims5
A method for reversibly binding at least one nucleic acid molecule to at least one paramagnetic particle comprising:
- (a) providing a suspension of at least one paramagnetic particle in an acidic solution;
- and
- (b) combining said suspension with at least one nucleic acid molecule such that said at least one nucleic acid molecule is reversibly bound to said at least one paramagnetic particle.
Dependencies are inferred from the claim text.