Stabilization of metal conjugates
AssigneeRoche Diagnostics GmbH
InventorsAlfons Nichtl, Peter Sluka
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Abstract
The invention concerns a composition comprising colloidal particles to the surface of which biomolecules are adsorbed, wherein the composition additionally contains a polyethylene glycol substituted by thiol or/and disulfide groups. This composition can be used as a detection reagent in immunological test methods.
Claims20
Colloidal particles to the surface of which are co-adsorbed:
- 1) biomolecules and 2) polyethylene qlycol substituted by thiol and/or disulfide groups.
A composition consisting essentially of colloidal particles with co-adsorbed substituted polyethylene glycol and biomolecules .
A process for making colloidal particles with co-adsorbed biomolecules and polyethylene glycol substituted by thiol or/and disulfide groups, said process comprising adding to said colloidal particles and biomolecules a polyethylene glycol substituted with thiol or/and disulfide groups.
Dependencies are inferred from the claim text.