Controlled release of pharmaceuticals in the anterior chamber of the eye
OwnerMiles A. Galin, Joseph C. Salamone +1inventors
InventorsMiles A. Galin, Joseph C. Salamone, Stanley C. Israel
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Abstract
The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of pharmaceuticals, including miotic, mydriatic, or anesthetic agents.
Claims36
A composition for intracameral use in opthalmologic surgery comprising a viscoelastic polymer and an effective amount of an anesthetic agent.
A composition for use in ophthalmology surgery comprising a viscoelastic polymer, an anesthetic agent, and a drug, wherein the viscoelastic polymer, the anesthetic agent, and the drug form an ionic viscoelastic polymer-anesthetic-drug complex, wherein the drug is selected from the group consisting of miotic and mydriatic agents.
A method of maintaining the structural integrity of the anterior chamber of the eye during surgery while concurrently providing anesthesia, comprising administering a viscoelastic polymer and a therapeutically effective amount of an anesthetic agent to be administered to a subject in need thereof.
Dependencies are inferred from the claim text.