Mass spectrometer
AssigneeHitachi, Ltd.
InventorsTakayuki Nabeshima, Minoru Sakairi, Yasuaki Takada, Yukiko Hirabayashi, Hideaki Koizumi
Life of this patent
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Abstract
A semi-micro liquid chromatograph/mass spectrometer apparatus has an ion source. The space from the end portion of a flow passage of a liquid chromatograph shell to a vaporization portion is closed so as to prevent the inflow of a gas from outside the ion source into the space. Further, the nebulization and vaporization portions are joined together and heated by a common heater. Dilution of a sample to be analyzed is prevented, and high sensitivity detection becomes possible in a low velocity liquid chromatograph/mass spectrometer.
Claims13
A mass spectrometer comprising means for supplying a sample solution consisting of a solvent and a solute, ionization means for ionizing said sample solution and means for analyzing the mass of ions generated by said ionization means, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- and
- a heater for heating said needle electrode.
A mass spectrometer comprising means for supplying a sample solution consisting of a solvent and a solute, ionization means for ionizing said sample solution and means for analyzing a mass of ions generated by said ionization means, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- means for maintaining said needle electrode being kept at a temperature higher than the boiling point of said solvent.
A mass spectrometer, comprising means for supplying a sample solution consisting of a solvent and a solute, nebulization means for nebulizing said sample solution, ionization means for ionizing said sample solution and means for analyzing a mass of ions generated by said ionization means, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- and
- a screen member for preventing a let of said sample solution formed by said nebulization means from reaching said needle electrode,
- wherein said screen member is an insulator containing therein said needle electrode.
A mass spectrometer, comprising:
- a capillary for supplying a solution containing a sample;
- a member for holding said capillary and a needle electrode for ionizing said sample-containing solution eluted from said capillary to provide ionized molecules, said holding member having a heater;
- and
- an analyzer region receiving said ionized molecules for conducting mass spectrometry of said ionized molecules of said sample;
- wherein said capillary is inserted in a hole in said holding member and an insertion length is adjusted by a collar stoppper fit around a periphery of said capillary and engaging said holding member.
A mass spectrometer comprising means for supplying a sample solution of a solvent and a solute, an ionizer that ionizes vaporized molecules and an analyzing region that receives ionized molecules of a sample solution for conducting mass spectrometry of ionized molecules, said mass spectrometer including:
- a needle electrode for generating corona discharge in said ionizer;
- and
- a heater for heating said needle electrode.
A mass spectrometer comprising means for supplying a sample solution of a solvent and a solute, an ionizer that ionizes vaporized molecules and an analyzing region that receives ionized molecules of a sample solution for conducting mass spectrometry of ionized molecules, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- means for maintaining said needle electrode being kept at a temperature higher than the boiling point of said solvent.
A mass spectrometer, comprising means for supplying a sample solution of a solvent and a solute, an ionizer that ionizes vaporized molecules and an analyzing region that receives ionized molecules of a sample solution for conducting mass spectrometry of ionized molecules, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- and
- a screen member for preventing a let of said sample from being blown into said needle electrode,
- wherein said screen member is an insulator containing therein said needle electrode.
A mass spectrometer comprising a supplier that supplies a sample solution consisting of a solvent and a solute, an ion source that ionizes said sample solution, and an analyzer that analyzes a mass of ions generated by said ion source, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- and
- a heater for heating said needle electrode.
A mass spectrometer comprising a supplier that supplies a sample solution consisting of a solvent and a solute, an ion source that ionizes said sample solution, and an analyzer that analyzes a mass of ions generated by said ion source, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- and
- a heating portion to maintain said needle electrode to be kept at a temperature higher than a boiling point of said solvent.
A mass spectrometer, comprising a supplier that supplies a sample solution consisting of a solvent and a solute, a nebulizer that nebulizes said sample solution, an ion source that ionizes said sample solution, and an analyzer that analyzes a mass of ions generated by said ion source, said mass spectrometer including:
- a needle electrode for generating corona discharge;
- and
- a screen member for preventing a jet of said sample solution formed by said nebulizer from reaching said needle electrode,
- wherein said screen member is an insulator containing therein said needle electrode.
Dependencies are inferred from the claim text.