Process for the manufacture of acetonylbenzamides
AssigneeRohm and Haas Company
InventorsEnrique Luis Michelotti, Heather Lynnette Rayle, Randall Wayne Stephens, William Joseph Zabrodski
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Abstract
Novel routes for the preparation of acetonylbenzamides are provided by the reaction of an amine and acyl chloride. Novel routes to various intermediates used in the manufacture of acetonylbenzamides are also disclosed.
Claims1
A method for producing a benzoyl chloride of the formula ##STR18## comprising the chlorination to 30-50% conversion of p-toluoyl chloride in the presence of chlorine gas and an aluminum chloride or antimony (V) chloride catalyst to provide a mixture of chlorinated toluoyl chlorides comprising 3,5-dichloro-4-methylbenzoyl chloride, 3-chloro-4-methylbenzoyl chloride and 2,5-dichloro-4-methylbenzoyl chloride as shown by the formulas ##STR19## wherein G.sub.1 and G.sub.2 ate independently selected from H and Cl;
- distilling said mixture of chlorinated toluoyl chlorides to recover the 3,5-dichloro-4-methylbenzoyl chloride from the 3-chloro-4-methylbenzoyl chloride and 2,5-dichloro-4-methylbenzoyl chloride;
- and
- recycling the 3-chloro-4-methylbenzoyl chloride for further chlorination.
Dependencies are inferred from the claim text.