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US 5,969,125 AGranted
Secreted proteins and polynucleotides encoding them
AssigneeGenetics Institute, Inc.
InventorsKenneth Jacobs, John M. McCoy, Edward R. LaVallie, Lisa A. Racie, David Merberg, Maurice Treacy, Vikki Spaulding
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Abstract
Novel polynucleotides and the proteins encoded thereby are disclosed.
Claims21
An isolated polynucleotide selected from the group consisting of:
- (a) a polynucleotide comprising the nucleotide sequence of SEQ ID NO:2;
- (b) a polynucleotide comprising the nucleotide sequence of SEQ ID NO:2 from nucleotide 185 to nucleotide 387;
- (c) a polynucleotide comprising the nucleotide sequence of the full length protein coding sequence of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- (d) a polynucleotide encoding the full length protein encoded by the cDNA insert of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- (e) a polynucleotide comprising the nucleotide sequence of the mature protein coding sequence of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- (f) a polynucleotide encoding the mature protein encoded by the cDNA insert of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- (g) a polynucleotide encoding a protein comprising the amino acid sequence of SEQ ID NO:3, said sequence of SEQ ID NO:3 being the sequence encoded by the cDNA insert of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- (h) a polynucleotide encoding a protein comprising the amino acid sequence of SEQ ID NO:3 from amino acid 1 to amino acid 28, said sequence of SEQ ID NO:3 being the sequence encoded by the cDNA insert of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- and
- (i) a polynucleotide which is an allelic variant of a polynucleotide of (a)-(f) above.
7 more elements
An isolated protein, wherein said protein comprises an amino acid sequence selected from the group consisting of:
- (a) the amino acid sequence of SEQ ID NO:3;
- (b) the amino acid sequence of SEQ ID NO:3 from amino acid 1 to amino acid 28;
- and
- (c) the amino acid sequence encoded by the cDNA insert of clone AP224.sub.-- 2 deposited under accession number ATCC 98115;
- said sequence of SEQ ID NO:3 being the sequence encoded by the cDNA insert of clone AP224.sub.-- 2 deposited under accession number ATCC 98115, said protein being substantially free from other mammalian proteins.
2 more elements
An isolated gene corresponding to the cDNA sequence of SEQ ID NO:2, SEQ ID NO:1 and SEQ ID NO:4.
Dependencies are inferred from the claim text.