Nucleic acid molecules derived from a brain tissue library
AssigneeMillennium BioTherapeutics, Inc.
InventorDouglas A. Holtzman
Life of this patent
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Abstract
The invention provides nucleic acid molecules derived from a brain tissue library. The nucleic acid molecules are used in applications such as diagnostic methods, screening assays and as hybridization probes and primers.
Claims16
An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- and
- b) the complement of SEQ ID NO:
- 1.
An isolated nucleic acid molecule consisting of a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- and
- b) the complement of SEQ ID NO:
- 1.
An isolated portion of a nucleic acid molecule consisting of a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- and
- b) the complement of SEQ ID NO:
- 1,
- wherein the portion is at least about 10 nucleotides in length.
An isolated portion of a nucleic acid molecule consisting of a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- and
- b) the complement of SEQ ID NO:
- 1,
- wherein the portion is at least 20 nucleotides in length.
A method for assaying the presence of a nucleic acid molecule in a sample, comprising contacting said sample with a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- b) the complement of SEQ ID NO:
- 1;
- c) a portion of SEQ ID NO:
- 1 which is at least 10 nucleotides in length;
- and
- d) a portion of the complement of SEQ ID NO:
- 1 which is at least 10 nucleotides in length
- under conditions appropriate for specific hybridization.
A nucleic acid molecule comprising a nucleotide sequence which is greater than about 75 percent identical to a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- and
- b) the complement of SEQ ID NO:
- 1.
A nucleic acid molecule which hybridizes under high stringency conditions to a nucleotide sequence selected from the group consisting of:
- a) SEQ ID NO:
- 1;
- and
- b) the complement of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.